Guohua An Selected Research

oxfendazole

1/2022	Population Pharmacokinetic-Pharmacodynamic Model of Oxfendazole in Healthy Adults in a Multiple Ascending Dose and Food Effect Study and Target Attainment Analysis.
1/2021	Population Pharmacokinetic Model of Oxfendazole and Metabolites in Healthy Adults following Single Ascending Doses.
10/2020	Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Adults in an Open-Label Phase 1 Multiple Ascending Dose and Food Effect Study.
1/2019	Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Volunteers: a Randomized, Placebo-Controlled First-in-Human Single-Dose Escalation Study.

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Guohua An Research Topics

Disease

11	Breast Neoplasms (Breast Cancer) 10/2019 - 09/2008
7	Neoplasms (Cancer) 10/2019 - 09/2008
5	Tuberculosis (Tuberculoses) 11/2020 - 07/2015
4	Body Weight (Weight, Body) 01/2022 - 07/2015
4	Critical Illness (Critically Ill) 01/2020 - 03/2015
3	Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis) 01/2020 - 01/2019
2	Surgical Wound Infection 02/2022 - 03/2021
2	Neurocysticercosis 10/2020 - 01/2019
2	Diabetic Neuropathies (Diabetic Neuropathy) 01/2020 - 10/2015
2	Osteoporosis 01/2019 - 01/2016
2	Neuralgia (Stump Neuralgia) 10/2015 - 03/2015
2	Renal Insufficiency (Renal Failure) 05/2015 - 03/2015
1	Parasitic Diseases (Parasitic Disease) 01/2022
1	Communicable Diseases (Infectious Diseases) 01/2021
1	Neonatal Anemia 10/2019
1	Hemolysis 07/2019
1	Lactic Acidosis 01/2017
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2016
1	Metabolic Bone Diseases (Osteopenia) 01/2016
1	Male Infertility (Male Sterility) 10/2015
1	Rheumatoid Arthritis 10/2015
1	Pain (Aches) 10/2015
1	Hemorrhage 03/2015
1	Gout 03/2015

Drug/Important Bio-Agent (IBA)

8	Proteins (Proteins, Gene)FDA Link 10/2019 - 07/2010
4	oxfendazoleIBA 01/2022 - 01/2019
4	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 10/2019 - 12/2014
4	biochanin AIBA 11/2011 - 09/2008
3	benzimidazoleIBA 01/2021 - 01/2019
3	AnthelminticsIBA 01/2021 - 01/2019
3	Pharmaceutical PreparationsIBA 01/2020 - 12/2014
3	FlavonoidsIBA 04/2011 - 09/2008
2	Antiparasitic Agents (Antiparasitics)IBA 01/2022 - 10/2020
2	Anti-Bacterial Agents (Antibiotics)IBA 03/2021 - 01/2018
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2016
2	AcidsIBA 01/2017 - 01/2016
2	GlycosidesIBA 10/2015 - 04/2011
2	T-Type Calcium Channels (T-Type Calcium Channel)IBA 10/2015 - 03/2015
2	4- chloro- 2- fluoro- N- (2- fluorophenyl)- 5- (hexahydropyrrolo(1,2- a)pyrazin- 2(1H)- ylcarbonyl)benzenesulfonamideIBA 10/2015 - 03/2015
2	Fondaparinux (Arixtra)FDA Link 05/2015 - 03/2015
2	ATP-Binding Cassette Transporters (ABC Transporters)IBA 12/2014 - 09/2014
2	Adenosine Triphosphate (ATP)IBA 09/2014 - 03/2011
2	QuercetinIBA 03/2011 - 09/2008
2	Mitoxantrone (Novantrone)FDA LinkGeneric 07/2010 - 07/2010
1	Cefazolin (Ancef)FDA LinkGeneric 02/2022
1	Hemoglobins (Hemoglobin)IBA 01/2022
1	sultamicillin (ampicillin-sulbactam)FDA LinkGeneric 03/2021
1	Isoniazid (Ftivazide)FDA LinkGeneric 11/2020
1	Linezolid (Zyvox)FDA Link 01/2020
1	Gabapentin (Neurontin)FDA LinkGeneric 01/2020
1	Urea (Carbamide)FDA LinkGeneric 01/2020
1	Epoxide HydrolasesIBA 01/2020
1	Isonicotinic Acids (Isonicotinic Acid)IBA 01/2020
1	Ethionamide (Trecator-SC)FDA Link 01/2020
1	nilotinib FDA Link 10/2019
1	Erythropoietin FDA Link 10/2019
1	SolutionsIBA 07/2019
1	FluoroquinolonesIBA 01/2019
1	Cycloserine (Seromycin)FDA Link 01/2019
1	5-hydroxyhexanoic acidIBA 01/2019
1	Alanine (L-Alanine)FDA Link 01/2019
1	Taurine FDA Link 01/2019
1	LactamsIBA 01/2018
1	Dichloroacetic AcidIBA 01/2017
1	Pyruvate Dehydrogenase Acetyl-Transferring KinaseIBA 01/2017
1	Estrogens (Estrogen)FDA Link 01/2016
1	Nonesterified Fatty Acids (NEFA)IBA 01/2016
1	LipidsIBA 01/2016
1	Oleic Acid (Oleate)IBA 01/2016
1	Fatty Acids (Saturated Fatty Acids)IBA 10/2015
1	triptolideIBA 10/2015
1	Pregabalin (Lyrica)FDA Link 10/2015
1	Calcium Channels (Calcium Channel)IBA 10/2015
1	Analgesics (Analgesic Drugs)IBA 10/2015
1	Calcium Channel Blockers (Blockers, Calcium Channel)IBA 10/2015
1	Levofloxacin (Levaquin)FDA Link 07/2015
1	Uric Acid (Urate)IBA 03/2015
1	EnzymesIBA 12/2014
1	dimethylethylsilylimidazoleIBA 12/2014
1	kaempferolIBA 04/2011
1	robininIBA 04/2011
1	5,7-dimethoxyflavoneIBA 07/2010
1	kaempferideIBA 07/2010
1	epigallocatechin gallate (epigallocatechin-3-gallate)IBA 09/2008

Therapy/Procedure

5	Therapeutics 10/2019 - 09/2014
2	Renal Replacement Therapy (Therapies, Renal Replacement) 05/2015 - 03/2015
1	Duration of Therapy 01/2020
1	Catheters 01/2020
1	Oral Administration 01/2016
1	Chinese Traditional Medicine (Traditional Chinese Medicine) 10/2015
1	Drug Therapy (Chemotherapy) 09/2014